Well Id say 2 250's would be to much unless your planning on keeping a sps dominated tank. I have the same dimension tank and I run two 150's on it with T5 supplements for actinic and thats more then enough for my LPS/Softies/Anemone. With two MH, even my 150's, heat is an issue even in our climate, and I would assume two 250's in a closed hood would be even worst. You would need a lot of computer fans and would probably be evaporating off over 2gals a day, I'm close to that myself.
I guess what Im trying to say is if I did it again Id go LED or if money was to tight T5... I love the look of MH's but in a closed hood they are rough. If you have the room to lift them off your tank 18" then you may be golden.
Im rambling.
Hope it helped a bit.
Cheers!