I lot does depend on the quality of the filters/membrane and how dirty your water is. Nitro has 180 going in, I have 119. So a bit of a difference. I think those come with a tds inline meter, so really, as long as your numbers are good, your filters are good. I have a 75gpd and the pre/post filters and DI lasted a year, and actually were still showing 0TDS but I swapped them to save wear and tear on the membrane.
A good blackflush kit supposedly works well too, I use mine, and maybe it does something good, hard to tell honestly.